Analysis of Pharmaceutical Interventions Administered to Inpatients who were taking Dietary Supplements and Establishment of a Management Algorithm

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  • Adachi Makiko
    Department of Hospital Pharmacy, Faculty of Medicine, Tottori University
  • Takane Hiroshi
    Department of Hospital Pharmacy, Faculty of Medicine, Tottori University
  • Shinozuka Kazumasa
    Department of Pharmacology, School of Pharmacy and Pharmaceutical Science, Mukogawa Women's University
  • Moriki Kuniaki
    Department of Hospital Pharmacy, Faculty of Medicine, Tottori University
  • Ogawa Katsuhiro
    Department of Hospital Pharmacy, Faculty of Medicine, Tottori University
  • Kaneda Tatsuya
    Department of Hospital Pharmacy, Faculty of Medicine, Tottori University
  • Shiinoki Yoshikazu
    Department of Hospital Pharmacy, Faculty of Medicine, Tottori University
  • Shimada Miki
    Department of Hospital Pharmacy, Faculty of Medicine, Tottori University

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  • 健康食品利用入院患者に対する薬学的介入内容の分析と管理アルゴリズムの構築

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Abstract

Pharmaceutical interventions are sometimes ineffective in patients who take dietary supplements (DS) because the medical staff providing the treatment are not aware that the patient is taking DS.<br>This study was performed to analyze pharmaceutical interventions administered to inpatients taking DS. The pharmaceutical interventions were chosen by the pharmacists in charge of each ward with the support of a nutritional representative・supplement adviser. Then, we tried to develop a systematic pharmaceutical management strategy for patients who were taking DS based on this analysis.<br>This study examined 32 interventions (involving 28 patients including 3 patients who were treated multiple times), and 20 patients (63%) who stopped taking DS during the study period.<br>The most serious issues that arose during the interventions included DS-drug interactions (6, 19%), issues associated with perioperative management (6, 19%), direct DS-induced damage (including suspected cases) (5, 16%), and conditions that required immediate attention (5, 16%).<br>We found that by examining the patients' characteristics including their disease status and any medications that they were taking we were able to avoid drug treatment failure. This indicates that it is necessary for pharmacists to be aware of patients' use of DS.<br>We developed a systematic “pharmaceutical management algorithm” based on our analysis of the above-mentioned pharmaceutical interventions. We consider that this algorithm will aid the selection of pharmaceutical management strategies by pharmacists．In future, we will improve the practicality and efficacy of the algorithm based on feedback from clinical pharmacists.

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