5種類の硝酸イソソルビド徐放性製剤の製剤評価
書誌事項
- タイトル別名
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- Evaluation of five sustained release preparations of isosorbide dinitrate.
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説明
A weight variation test, a content uniformity test, and a dissolution test were carried out, in five commercial sustained release preparations of isosorbide dinitrate (ISDN).The weight variation test and the content uniformity test with the preparations showed a small variation in each case.Their release patterns including release profile, release rate, and mean dissolution time (MDT) of ISDN were different among them.Percent of ISDN released in 8 h decreased in the following order;<BR>Kalliant TP>Nitorol R>Helpinin-R>Frandol>Rifatac-L, and MDT increased in the same order.<BR>Significant differences in cumulative percent of drug released were observed among some lots of Helpinin-R, Kalliant TP and Rifatac-L while no such difference was noted in Nitorol R and Frandol.
収録刊行物
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- 病院薬学
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病院薬学 15 (6), 409-416, 1989
一般社団法人 日本医療薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204775779968
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- NII論文ID
- 110001798644
- 130004103035
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- NII書誌ID
- AN00002794
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- ISSN
- 21859477
- 03899098
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- NDLデジコレ(旧NII-ELS)
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可