大黄および漢方エキスか粒剤中のセンノサイド含量

書誌事項

タイトル別名
  • Sennosides contents in Rhei Rhizoma and the Chinese medicinal extracts.

説明

The quantitative analysis of sennosides in Rhei Rhizoma and Chinese medicinal preparations containing Rhei Rhizoma was investigated. Sennoside-A, -B and 8-glucosyl rhein of main components were separated and determined by high performance liquid chromatography (HPLC) on LiChrosorb RP-18 column with a mobil phase of MeOH: pH 3.4 succinate-borate buffer (1: 2).<BR>Compositions of twenty-two market drugs originated from five species Rhei Rhizoma of Kinmon Daio, Gao, Batei Daio, Kohoku Daio and Rhei Rhizoma pulv. were as follows (in mg/g): sennoside-A 2.19-28.12, sennoside-B 0.63-16.40, 8-glucosyl rhein 1.33-19.43. The large content variations probably result in the difference of purgative action.<BR>Quality tests were made on fourteen kinds of Chinese medicinal preparations containing Rhei Rhizoma. The quality of Chinese medicinal preparation is changed by crude drugs and preparation methods such as extraction, concentration and others.

収録刊行物

  • 病院薬学

    病院薬学 13 (1), 1-5, 1987

    一般社団法人 日本医療薬学会

詳細情報 詳細情報について

  • CRID
    1390001204777884928
  • NII論文ID
    130004298996
  • DOI
    10.5649/jjphcs1975.13.1
  • ISSN
    21859477
    03899098
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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