書誌事項
- タイトル別名
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- Zinc supplementation improves ALT level in chronic hepatitis C patients during combination therapy of PEG-interferon .ALPHA.-2b and ribavirin
この論文をさがす
説明
We investigated the effects of zinc supplementation on the clinical observations in chronic hepatitis C patients during PEG-interferon α-2b plus ribavirin (PEG-IFN/R) therapy. Patients were randomly allocated to receive daily 150 mg polaprezinc (Zn group, n=11) or no supplement (control, n=12) in addition to PEG-IFN/R therapy and daily antioxidant vitamin supplementation (300 mg of vitamin E and 600 mg of vitamin C). Ten of 11 patients (91%) in Zn group and 7 of 12 (58%) control patients showed decrease in ALT levels (</=35 U/l) after 8 weeks of therapy. This observation indicates that polaprezinc supplementation may induce antioxidative functions in liver which resulted in improvement of hepatocyte injury during PEG-IFN/R therapy.
収録刊行物
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- 肝臓
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肝臓 47 (3), 165-, 2006
一般社団法人 日本肝臓学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390001204790341504
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- NII論文ID
- 10017560591
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- NII書誌ID
- AN00047770
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- COI
- 1:CAS:528:DC%2BD28XltVGit70%3D
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- ISSN
- 18813593
- 04514203
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- 本文言語コード
- ja
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可
