A case of multilocular cystic hepatocellular carcinoma without underlying cirrhosis.

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  • MIZUNO Yasutsugu
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • NOTSUMATA Kazuo
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • FURUSAWA Akihiko
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • MOTOO Yoshiharu
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • HIRAI Nobuyuki
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • MATSUI Osamu
    Department of Radiology, School of Medicine, Kanazawa University
  • IZUMI Ryohei
    The Second Department of Surgery, School of Medicine, Kanazawa University
  • NODA Yatsugi
    The Second Department of Pathology, School of Medicine, Kanazawa University
  • UNOURA Masashi
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • TANAKA Nobuyoshi
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • KOBAYASHI Kenichi
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • HATTORI Nobu
    The First Department of Internal Medicine, School of Medicine, Kanazawa University
  • NAKANUMA Yasuni
    Department of Internal Medicine, Toyama Rosai Hospital

Bibliographic Information

Other Title
  • 多発性嚢胞性病変を呈した肝硬変非合併肝細胞癌の１例

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Abstract

A 52-year-old woman was admitted to our hospital because of marked hepatomegaly. The findings of Ultrasound, CT scan and Angiography suggested a hepatocellular carcinoma (HCC) associated with multiple cysts. The open biopsy was performed to confirm the diagnosis. A huge massive tumor about 10cm in diameter partially associated with multiple cystic lesions was observed in the right lobe of liver at laparotomy. The histological finding of the tumor was HCC, and the nontumorous part was almost normal liver.<BR>TAE, intraarterial administration of 5-FU and CDDP, and oral administration of UFT were performed, resulting in the improvement of hepatomegaly (reduction rate: 63.8%, partial response). The marked reduction of the tumor and cystic lesions was shown using CT scan. It is characteristic in this case that HCC developed in the normal liver and was associated with multiple cystic lesions. This case seems to be interesting from the viewpoint of the pathogenesis of multicystic HCC and the therapeutic effect of TAE and chemotherapy.

Journal

  • Kanzo

    Kanzo 30 (1), 75-81, 1989

    The Japan Society of Hepatology

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