Efficacy of CE14 (human placenta preparation) in a double blind trial on chronic liver diseases
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- UEDA Hideo
- Central Hosp. Japanese National Railways
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- OKUMURA Hidemasa
- lst Dept. of Internal Med., Nippon Medical School
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- HORIGUCHI Masaharu
- Dept. of Internal Med. (Digestive Organs), Dai-san Hosp., The Jikei Univ. School of Med.
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- NAMIHISA Toshihiko
- Dept. of Internal Med. (Digestive Organs), Juntendo Univ. School of Med.
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- ONODA Taikobo
- Dept. of Sociology, St. Paul's Univ.
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- IWAMURA Kenichiro
- lst Dept. of Internal Med., Tokyo Medical College
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- UENO Yukihisa
- Dept. of Internal Med., Mishuku Hosp., Tokyo
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- OKUDA Kunio
- lst Dept. of Internal Med., Faculty of Med., Univ.
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- OHMORI Ryoga
- Dept. of Internal Med., Senso-Ji Hosp.
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- KOBAYASHI Sadao
- lst Dept. of Internal Med., School of Med., Gunma Univ.
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- SAKAI Kazuo
- Dept. of Internal Med., Sakai Municipal Hosp.
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- TAKINO Tatsuro
- 3rd Dept. of Internal Med., Kyoto Prefectural Univ.
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- TSUCHIYA Masaharu
- Dept. of Internal Med., School of Med., Keio Univ.
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- HASHIMOTO Shuji
- 2nd Dept. of Internal Med., School of Med., Kagoshima Univ.
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- HIROSHIGE Kaichiro
- Dept. of Internal Med., Fukuoka Saisei-kai General Hosp.
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- YANO Mikio
- Dept. of Internal Med., Matsuyama Red Cross Hosp.
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- YAMAMOTO Shigeru
- Dept. of Internal Med., The Medical Institute of Sasaki Foundation, Kyoundo Hosp.
Bibliographic Information
- Other Title
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- 二重盲検によるCE-14の慢性肝疾患に対する効果
- ニジュウ モウケン ニ ヨル CE-14 ノ マンセイ ギモ シッカン ニ タイスル コウカ
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Description
CE14 (L), hydrolized cold human placenta, contains various amino acids. As the action of L, lipotropic function, accelerating activity on tissue respiration, action promoted hepatic regeneration, and others were already reported by the experimental studies. The present study was to know whether or not L was an effective drug for the treatment of chronic liver diseases. The patients were divided in two groups at random in double blind method. Saline solution was used as placebo. In group 1, the injection of L was performed for two weeks. After that the placebo was used for two weeks, and the study was repeated once more. Group 2 received the injection of placebo at first. For the next two weeks they were injected L. After that the process was done once more the same as group 1. The liver function tests were examined every two weeks, and their levels before and after two weeks were compared. GOT and GPT in both groups decreased in the period of the administration of L and it was statistically significant. In contrast, no significant decreases of GOT and GPT were obtained in the placebo period of both groups. Consequently, it is suggested that L is effective in patients with chronic liver diseases.
Journal
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- Kanzo
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Kanzo 15 (3), 162-171, 1974
The Japan Society of Hepatology
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Details 詳細情報について
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- CRID
- 1390001204791188480
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- NII Article ID
- 130000871974
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- NII Book ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL BIB ID
- 7519750
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL Search
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed