重症急性肝炎にて発症し,抗リン脂質抗体症候群の合併が疑われた自己免疫性肝炎の1例

書誌事項

タイトル別名
  • A case of autoimmune hepatitis masquerading as acute hepatitis and accompanied by probable antiphospholipid syndrome.

この論文をさがす

抄録

A 51-year-old woman with a past history of acute obstruction of central retinal artery presented with general malaise and jaundice. In addition to severe liver dysfunction, hypergammaglobulinemia (2.8g/dl), positive of antinuclear antibody (speckled pattern ×160), biologically false positive serologic test for syphilis (slide test) and IgM anticardiolipin antibody (aCL) were also disclosed. Based on the diagnostic criteria offered by the Japanese Ministry of Welfare as well as International Autoimmune Hepatitis (AIH) Group, this case was thought of AIH masquerading as serious acute hepatitis, and accompanied by presumptive antiphospholipid syndrome (APS). Though the hepatitis became worse with hepatic encephalopathy, treatments with corticosteroid and plasma exchange produced marked improvement. Liver needle biopsy revealed acute hepatitis of confluent necrosis type. This case may raise some intriguing points concerning the deduced undesirable influence of APS on acute hepatitis, and the meaning of aCL which was detected under serious liver dysfunction.

収録刊行物

  • 肝臓

    肝臓 37 (12), 744-748, 1996

    一般社団法人 日本肝臓学会

被引用文献 (1)*注記

もっと見る

参考文献 (20)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ