Immunohistochemical investigation of hepatitis B virus (HBV) associated antigens in liver tissues in asymptomatic HBs antigen carrier associated with simultaneous hepatitis A virus (HAV) infection
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- HIGUCHI Kiyohiro
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- KOJIMA Takashi
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- AOYAMA Keiichi
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- MATSUI Shinjiro
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- YASUYAMA Toshihumi
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- KONDA Takehiko
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- SHIBATA Mitsugu
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- ICHIDA Takafumi
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- NAKANO Mamoru
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- INOUE Kyoichi
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- SASAKI Hiroshi
- The 3rd Department of Internal Medicine, Toyama Medical and Pharmaceutical University
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- IMOTO Susumu
- Department of Internal Medicine, Kobe Shinko Hospital
Bibliographic Information
- Other Title
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- HBs抗原キャリアーに重感染したA型急性肝炎症例の検討 特にHBV関連抗原の組織免疫学的検討
- HBs コウゲン キャリアー ニ ジュウ カンセンシタ Aガタ キュウセイ カ
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Abstract
In three asymptomatic HBs antigen carriers infected with HAV the changes of serum HBV associated antigen and antibody system and HBV associated antigens in liver tissue were investigated.<BR>1) In serum, HBs antigen titer was low in acute phase of superimposed type A viral hepatitis and increased in recovery phase. Anti-HBc titer showed no similar changes. HBe antigen and anti-HBe revealed almost the same level throughout the course.<BR>2) In liver tissue, HBs antigen positive hepatocyte was rare or disappeared in acute phase of superimposed type A viral hepatitis and increased distinctly in recovery and healing phase. One case revealed marked membranous localization of HBs antigen in recovery phase. HBc and HBe antigens were rare in acute phase and increased in healing phase in serum HBe antigen positive case.<BR>3) It is suggested that the changes of HBs antigen titer in serum reflected amounts of HBs antigen produced in liver tissue. However, changes of serum HBe antigen titer and amount of HBe antigen in hepatocytes showed no pararell relation.
Journal
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- Kanzo
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Kanzo 24 (2), 149-160, 1983
The Japan Society of Hepatology
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Keywords
Details 詳細情報について
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- CRID
- 1390001204792189824
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- NII Article ID
- 130000879093
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- NII Book ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL BIB ID
- 2623454
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed