Studies on Serum Alkaline Phosphatase Activities and Isoenzymes in Patients with Hepatocellular Carcinoma.

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  • NAWATA Junsuke
    First Division, Department of Internal Medicine, Yamaguchi University School of Medicine
  • NISHIMURA Hideo
    First Division, Department of Internal Medicine, Yamaguchi University School of Medicine
  • HAYAKAWA Mikio
    First Division, Department of Internal Medicine, Yamaguchi University School of Medicine
  • ODAWARA Mitsuru
    First Division, Department of Internal Medicine, Yamaguchi University School of Medicine
  • TAKEMOTO Tadayoshi
    First Division, Department of Internal Medicine, Yamaguchi University School of Medicine

Bibliographic Information

Other Title
  • 肝細胞癌患者の血清alkaline phosphatase活性およびisoenzymeに関する研究
  • カン サイボウ ガン カンジャ ノ ケッセイ alkaline phospha
  • Comparison wiht Liver Scintigram
  • 肝シンチグラムとの対比

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Description

Serum alkaline phosphatase (ALP) activity of patients with hepatocellular carcinoma is higher than normal controls. To clarify the matters, serum ALP activities and isoenzymes were compared in sera of the patients with several types of hepatocellular carcinoma as to size, numbers and the localization of the tumor, using RI-scanning of the liver. <BR>As the results, a tendency of an increase in ALP activity and incidence of detection of macromolecular ALP was observed in the following occasions. A) When tumors were more multipie, B) when the localization of tumor was more toward hilus than periphery and C) when tumors was larger than smaller. <BR>These results indicate that ALP activity and/or incidence of detection of macromolecular ALP are related to the extent of the cholestatic area of the biliary system within the liver.

Journal

  • Kanzo

    Kanzo 18 (1), 37-43, 1977

    The Japan Society of Hepatology

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