「平田村肝炎」の病因に関する血清疫学的研究特にB型肝炎ウイルスとの関連において

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タイトル別名
  • Seroepidemiological Investigation of the Cause of so-called "Hirata-Mura Hepatitis" with Special Reference to Hepatitis B Virus Infection
  • ヒラタムラ カンエン ノ ビョウイン ニ カンスル ケッセイ エキガクテキ ケ

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説明

T-Area, where lived 244 persons in 52 families, was selected as a hepatitis prevalent area in Hirata-Mura (villege). Correspondingly, I-Area, where lived 275 persons in 75 families, was selected as a control area in the neighbor town, Ono-Machi. In T-Area, sera from 206 healthy persons (84.4%) in 49 families (94.2%) were collected, and in I-Area, 231 sera (84.0%) from 69 families (92.0%) were collected. HBsAg and anti-HBs were detected by means of R-PHA and PHA methods respectively. <BR>Carrier rate of HBsAg was 4.4% in T-Area and 0.9% in I-Area. Minimum exposure rate to HBV infection was calculated as high as 45.6% in T-Area, and 19.5% in I-Area. Familial extremely high accumulation of the history of HBV infection was recognized in T-Area, though non of the "family trees" studied showed any typical pattern of mother-to-child transmission. Subtype of HBsAg determined was all adr. HBeAg was found in 3 persons from T-Area, and 1 from I-Area.

収録刊行物

  • 肝臓

    肝臓 18 (6), 401-407, 1977

    一般社団法人　日本肝臓学会

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