Changing trends of genotypic distribution of hepatitis B virus in Mito, Japan (2001-2013)
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- Aikawa Tatsuya
- Aikawa Internal Medicine Hospital
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- Sugiyama Hiroaki
- Department of Gastroenterology, Tsukuba Memorial Hospital
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- Soeda Atsuko
- Department of Gastroenterology, Tsukuba Memorial Hospital
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- Ikezawa Kazuto
- Department of Gastroenterology, Tsukuba Memorial Hospital
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- Sato Tsutomu
- Sato Clinic
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- Tsuda Fumio
- Aikawa Internal Medicine Hospital
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- Ueno Chisato
- Aikawa Internal Medicine Hospital
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- Okamoto Hiroaki
- Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine
Bibliographic Information
- Other Title
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- 水戸地域におけるB型肝炎ウイルスの遺伝子型分布の変遷(2001~2013年)
- ミト チイキ ニ オケル Bガタ カンエンウイルス ノ イデンシガタ ブンプ ノ ヘンセン(2001~2013ネン)
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Abstract
To examine recent trends of acute infection with hepatitis B virus (HBV) in Mito, located in a non-Metropolitan area of Japan, serum samples obtained from 17 patients with acute hepatitis B (AHB) and 243 patients with chronic HBV infection during 2001-2013 were subjected to HBV genotyping. HBV genotype A (GtA) was detected in 3 (1%), GtB in 64 (26%) and GtC in 174 (72%) of patients with chronic HBV infection, while GtA was most prevalent (47%) among the AHB patients. Of note, GtA was found significantly more frequently in AHB patients during 2008-2013 than in those during 2001-2007 (64%vs. 17%, p<0.0001). These increasing trends of GtA HBV infection via sexual transmission emphasize the necessity of preventive education and measures.
Journal
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- Kanzo
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Kanzo 55 (10), 626-629, 2014
The Japan Society of Hepatology
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Keywords
Details 詳細情報について
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- CRID
- 1390001204793036928
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- NII Article ID
- 130004701706
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- NII Book ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL BIB ID
- 025861617
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed