A case of Wilson disease treated as schizophrenia for 20 years
-
- Kumei Shinsuke
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environment Health Department of Internal Medicine, IHI Harima Hospital
-
- Shibata Michihiko
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environment Health
-
- Honma Yuichi
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environment Health
-
- Matsuhashi Toru
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environment Health
-
- Hiura Masaaki
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environment Health
-
- Onishi Yutaka
- Department of Internal Medicine, IHI Harima Hospital
-
- Abe Shintaro
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environment Health
-
- Tabaru Akinari
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environment Health
-
- Harada Masaru
- Third Department of Internal Medicine, School of Medicine, University of Occupational and Environment Health
Bibliographic Information
- Other Title
-
- 長期にわたり統合失調症として加療されたウイルソン病の1例
- ショウレイ ホウコク チョウキ ニ ワタリ トウゴウ シッチョウショウ ト シテ カリョウ サレタ ウイルソンビョウ ノ 1レイ
Search this article
Abstract
A 42-year-old man, who had been diagnosed as schizophrenia due to memory disturbance, mental disorder and delusion of persecution at age of 20, was referred to our hospital due to progressive neurological symptoms and unknown liver dysfunction. He had previously been diagnosed as nonalcoholic steatohepatitis or drug-induced liver injury in some other hospitals. Later, he presented with difficulty in walking and akinesia like drug-induced parkinsonism.<br> On admission, his laboratory findings showed low levels of serum ceruloplasmin and the increase of 24-h urinary copper excretion. Kayser-Fleischer rings were demonstrated. Histological examination of the liver revealed cirrhosis and the hepatic copper concentration was elevated. MRI of the brain showed high-intensity signal area at the basal ganglia. We diagnosed him as Wilson disease and started treatment with trientine and zinc acetate, and also started rehabilitation. His mental disorder, parkinsonism and biochemical data have apparently improved after the initiation of the treatment.<br>
Journal
-
- Kanzo
-
Kanzo 53 (12), 814-820, 2012
The Japan Society of Hepatology
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390001204793480576
-
- NII Article ID
- 10031144305
-
- NII Book ID
- AN00047770
-
- ISSN
- 18813593
- 04514203
-
- NDL BIB ID
- 024164515
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- Abstract License Flag
- Disallowed