血中AFP動態からみたHepatomaの臨床分類

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書誌事項

タイトル別名
  • Clinical classification of hepatomas from changes in serum AFP levels
  • ケッチュウ AFP ドウタイ カラ ミタ Hepatoma ノ リンショウ ブ

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抄録

Quantitative determinations of serum alpha-fetoprotein (AFP) in 96 hepatoma patients have demonstrated three distinct patterns in the changes of AFP levels. In 50 patients weekly changes in serum AFP levels were more than about 10μg/ml or more (Group A). In the second group of 27 patients, a change of approximately 1000ng/ml in 3 to 4 months in AFP levels (Group B) was observed. The last group of 19 patients showed changes less than 200ng/ml in AFP levels throughout the course of the study (Group C). The survival time in Group A hepatoma patients was less than 6 months and from 6 to 18 months in Group B. Group C was composed of both, ones with long survival time from 24 to 40 months, and ones with short survival time less than 5 months. Histology revealed poorly differentiated cancer cells in Group A, moderately differentiated cells in Group B, and well differentiated cells as well as anaplastic cells in Group C.

収録刊行物

  • 肝臓

    肝臓 18 (11), 847-855, 1977

    一般社団法人　日本肝臓学会

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