A case of polymyositis concomitant with primary biliary cirrhosis simultaneously

DOI Web Site Web Site 47 References
  • Yokosuka Jun
    Department of Gastroenterology and Hepatology, The Jikei University School of Medicine
  • Ishikawa Tomohisa
    Department of Gastroenterology and Hepatology, The Jikei University School of Medicine
  • Nakao Yutaka
    Department of Gastroenterology and Hepatology, The Jikei University School of Medicine
  • Saruta Masayuki
    Department of Gastroenterology and Hepatology, The Jikei University School of Medicine
  • Hokari Atsushi
    Department of Gastroenterology and Hepatology, The Jikei University School of Medicine
  • Koike Kazuhiko
    Department of Gastroenterology and Hepatology, The Jikei University School of Medicine
  • Kitahara Takuya
    Department of Gastroenterology and Hepatology, The Jikei University School of Medicine
  • Harada Tohru
    Department of Pathology, The Jikei University School of Medicine
  • Hano Hiroshi
    Department of Pathology, The Jikei University School of Medicine
  • Tajiri Hisao
    Department of Gastroenterology and Hepatology, The Jikei University School of Medicine

Bibliographic Information

Other Title
  • 多発筋炎の診断時に原発性胆汁性肝硬変の併発を認めた1症例
  • 症例報告 多発筋炎の診断時に原発性胆汁性肝硬変の併発を認めた1症例
  • ショウレイ ホウコク タハツ キンエン ノ シンダンジ ニ ゲンパツセイ タンジュウセイ カンコウヘン ノ ヘイハツ オ ミトメタ 1 ショウレイ

Search this article

Abstract

A 54-year-old woman experienced continuous proximal muscle weakness in both legs 2 months before. Her laboratory findings showed remarkably high levels of serum creatine kinase, gamma-glutamyl transferase, and alkaline phosphatase. Magnetic resonance imaging (MRI) showed a high-intensity signal area at the vastus medialis muscle. Muscle biopsy findings revealed mononuclear inflammatory cell infiltration in endomysial connective tissue. On ultrasonography, we observed fibrosis change in the liver parenchyma. Histological examination of the liver revealed chronic nonsuppurative destructive cholangitis. We diagnosed the patient with polymyositis concurrent with primary biliary cirrhosis. Immediately after the patient was administered prednisolone and ursodeoxycholic acid, her muscle weakness and clinical data improved. Only a few previous studies have reported cases of polymyositis concurrent with primary biliary cirrhosis. Therefore, we believe that our study is unique and particularly useful for further study of autoimmune liver diseases.<br>

Journal

  • Kanzo

    Kanzo 53 (4), 216-224, 2012

    The Japan Society of Hepatology

References(47)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top