A case of elevated liver enzymes with MYH9 disorder

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  • Shiode Yuto
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Sakamori Ryotaro
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Yakushijin Takayuki
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Hikita Hayato
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Oze Tsugiko
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Yoshida Yuichi
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Tatsumi Tomohide
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Hiramatsu Naoki
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
  • Takehara Tetsuo
    Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine

Bibliographic Information

Other Title
  • MYH9遺伝子異常に伴う肝胆道系酵素上昇と考えられた一例
  • 症例報告 MYH9遺伝子異常に伴う肝胆道系酵素上昇と考えられた一例
  • ショウレイ ホウコク MYH9 イデンシ イジョウ ニ トモナウ カンタンドウケイ コウソ ジョウショウ ト カンガエラレタ イチレイ

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Abstract

<p>The case was a 48-year-old woman with MYH9 disorder. When she was 18 years old, she was suspected as having an autoimmune hepatitis (AIH) for the cause of her acute hepatitis. Because of insufficient effect of steroid therapy against her hepatitis, laparoscopic liver histological examination was performed at 48 years old, resulting in no abnormal finding. Any liver diseases including AIH did not correspond to her elevated liver enzyme. MYH9-related syndrome can cause an alteration of liver enzymes without histological findings. Her elevated liver enzyme was considered as the MYH9-related syndrome. MYH9 disorder should be kept in mind as a differential diagnosis for liver dysfunction.</p>

Journal

  • Kanzo

    Kanzo 57 (9), 475-480, 2016

    The Japan Society of Hepatology

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