Multiple hepatocellular adenomas: a case report

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  • Tamura Fumito
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Kawano Yutaka
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Miyanishi Koji
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Kubo Tomohiro
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Kamihara Yusuke
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Okagawa Yutaka
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Ishikawa Kazuma
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Takada Kohichi
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Hayashi Tsuyoshi
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Sato Tsutomu
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Sato Yasushi
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Kobune Masayoshi
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Takimoto Rishu
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine
  • Kawamoto Masaki
    Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine
  • Meguro Makoto
    Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine
  • Mizuguchi Toru
    Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine
  • Ogino Ziro
    Department of Clinical Pathology, Sapporo Medical University Hospital
  • Hasegawa Tadashi
    Department of Clinical Pathology, Sapporo Medical University Hospital
  • Yoneda Norihide
    Department of Radiology, Kanazawa University Graduate School of Medical Science
  • Sasaki Motoko
    Department of Human Pathology, Kanazawa University Graduate School of Medical Science
  • Kato Junji
    Department of Medical Oncology and Hematology, Sapporo Medical University School of Medicine

Bibliographic Information

Other Title
  • 肝生検で高分化型肝細胞癌との鑑別が困難であった多発肝細胞腺腫の1切除例
  • 症例報告 肝生検で高分化型肝細胞癌との鑑別が困難であった多発肝細胞腺腫の1切除例
  • ショウレイ ホウコク カンセイケン デ コウブンカガタ カン サイボウ ガン ト ノ カンベツ ガ コンナン デ アッタ タハツ カン サイボウセン シュ ノ 1 セツジョレイ

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Description

We report a rare case of multiple hepatocellular adenomas difficulty in ruling out well-differentiated hepatocellular carcinomas prior to resection. A 40s female was admitted to the hospital for examination of multiple liver tumors. CT and Gd-EOB-MRI showed that tumors were located in segment 2 and 5. We conducted a percutaneous tumor biopsy and tumor showed low atypical cells containing fat deposit. As the possibility of multiple hepatocellular carcinomas could not be denied, partial hepatectomy and RFA were done. All resected tumors showed a decreased expression of the liver fatty acid binding protein (L-FABP), and were finally diagnosed as multiple HNF1α-inactivated type hepatocellular adenomas. Multiple hepatocellular adenomas are rare tumors, so we report this case with review of the literatures.

Journal

  • Kanzo

    Kanzo 56 (11), 584-595, 2015

    The Japan Society of Hepatology

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