A case of advanced hepatocellular carcinoma with right hepatic artery diverging from superior mesenteric artery, effectively treated with hepatic arterial infusion chemotherapy using special reservoir system indwelling in aorta named System-I

Yoshida Michihiro, Okumura Fumihiro, Itano Satoshi, Monoe Takashi, Matsunami Kayoko, Inagaki Yusuke, Fujita Yasuaki, Mochiduki Hisato, Ogawa Kanto, Takada Hiroki, Sobue Satoshi, Seno Kyoji, Ito Kazuyuki

doi:10.2957/kanzo.49.512

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大動脈留置型特殊リザーバーシステム（System-I）を用いた肝動注化学療法が有用であった，転位右肝動脈を有する進行肝細胞癌の1例
症例報告大動脈留置型特殊リザーバーシステム(System-I)を用いた肝動注化学療法が有用であった,転位右肝動脈を有する進行肝細胞癌の1例
ショウレイホウコクダイドウミャクリュウチガタトクシュリザーバーシステム System I オモチイタカンドウチュウカガクリョウホウガユウヨウデアッタテンイミギカンドウミャクオユウスルシンコウカンサイボウガンノ 1レイ

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We hereby report a case of advanced hepatocellular carcinoma (HCC) with right hepatic artery (RHA) diverging from superior mesenteric artery (SMA), which completely responded to hepatic arterial infusion chemotherapy (HAIC) using special reservoir system indwelling in aorta named System-I. A 71-year-old man suffering from HCV-related liver cirrhosis was referred to our hospital to treat multiple HCCs in April 2005. Although transarterial chemolipiodolization was performed twice, the tumors progressed. Then, we undertook a therapy with low-dose cisplatin and 5-fluorouracil (low-dose FP) using System-I. We changed the position of the microcatheter alternatively in RHA and LHA every week. After 8 cycles of the low-dose FP therapy, computed tomography and angiography showed complete response of the HCCs, and levels of tumor markers (AFP and PIVKA-II) were normalized. We think that System-I is a very useful system that enables us to perform HAIC without changing the flow of replaced hepatic artery.<br>

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Kanzo

Kanzo 49 (11), 512-519, 2008

The Japan Society of Hepatology

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