Usefulness of ALBI grade in prediction of outcomes in patients with hepatitis B related hepatocellular carcinoma

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  • B型肝炎関連肝細胞癌の予後予測におけるALBI gradeの有用性
  • Bガタ カンエン カンレン カン サイボウ ガン ノ ヨゴ ヨソク ニ オケル ALBI grade ノ ユウヨウセイ

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Abstract

<p>We examined the usefulness of ALBI grade comparing to Child-Pugh classification in terms of prognostic significance in 266 HBs antigen-positive patients with initial hepatocellular carcinoma (HCC). ALBI grade was calculated from the serum albumin and bilirubin levels at the time of diagnosis. Survival rates after diagnosis were significantly different based on both ALBI grade and Child-Pugh class. The 5- and 10-year survival rates of ALBI grade 1 (77.8% and 64.8%, respectively) were significantly higher than those of Child-Pugh class A (60.8% and 48.5%, respectively, p=0.004). When focusing on patients with Child-Pugh class A, patients with ALBI grade 1 (n=122) showed significantly higher survival rate than those with ALBI grade 2 (n=66, p<0.001). ALBI grade was a useful prognostic indicator in patients with HBV-related HCC, which can further identify patients with Child-Pugh class A who had better liver function with favorable prognosis.</p>

Journal

  • Kanzo

    Kanzo 58 (7), 379-385, 2017

    The Japan Society of Hepatology

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