A case of reactive lymphoid hyperplasia of liver mimicking hepatocellular carcinoma: A case report

Yamamoto Kenta, Kumada Takashi, Kiriyama Seiki, Tanikawa Makoto, Hisanaga Yasuhiro, Toyoda Hidenori, Kanamori Akira, Tada Toshifumi, Kitabatake Syusuke, Hasegawa Ryouhei, Ito Takanori, Andou Yuusuke, Satta Yuusuke, Tanaka Tatsuya, Sone Yasuhiro, Fukusato Toshio

doi:10.2957/kanzo.54.755

We describe a case of hepatic reactive lymphoid hyperplasia (RLH) which developed in a 71-years old Japanese woman. At first she admitted to our hospital because of the esophageal varices rupture. After her treatment, she was found to have a nodule in the liver. Her hepatitis viral-associated antigen/antibody was negative and liver function tests and tumor markers were all within normal limits without her platelet count which was 24,000/μl. Gadolinium ethoxybenzyl-diethylenetriamine-enhanced magnetic resonance imaging (MRI) and Sonazoid-enhanced ultrasonography were suggestive of hepatocellular carcinoma (HCC). CT angiography showed classical HCC enhancement pattern that tumor had increased perfusion at computed tomography during hepatic arteriography (CTHA) and a perfusion defect at computed tomography during arterial portography (CTAP). But the tumor did not have the clearly corona enhancement. We diagnosed atypical HCC. The patient was subjected tolaparoscopic partial resection of the 6th segment of the liver and the final histological report showed idiopathic portal hypertension and RLH. She was discharged without complications. RLH is a rare benign lesion in the liver. This case is very difficult to get the preoperative diagnosis. But we have to collect the more information about RLH to avoid unnecessary surgery.

A case of reactive lymphoid hyperplasia of liver mimicking hepatocellular carcinoma: A case report

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