Clinical Effects of Oxiconazole Nitrate Cream on Dermatomycosis

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  • オキシコナゾールクリームの表在性真菌症に対する臨床効果

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Clinical effects on dermatomycosis were studiedusing a newly developed antifungal cream, which contained 1% oxiconazole nitrate, a newimidazole derivative. 44 patients were treated, comprising 23 with superficial tinea (6 withtinea pedis, 4 with tinea manus, 6 with tineacruris, and 7 with tinea corporis), 11 withcutaneous candidiasis (6 with intertriginous, and 5 with interdigital candidiasis), and 10 withpityriasis versicolor.<BR>The utility rate was 66.7% in patients withtinea pedis, 100% tinea manus, 100% tineacruris, and 85.7% tinea corporis, and 87.0%in all patients with superficial tinea. The utilityrate on cutaneous candidiasis revealed 100% inboth intertriginous candidiasis and interdigital candidiasis. Hundred percent utility rate wasalso noticed in pityriasis versicolor. No sideeffect was observed.<BR>Accordingly we assessed that the cream containing1% oxiconazole nitrate was a prominenttopical remedy against dermatomycosis withoutany side effects.

Journal

  • Skin research

    Skin research 26 (3), 711-720, 1984

    Meeting of Osaka Dermatological Association

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