甲殻類，軟体類，アニサキス，回虫，ゴキブリ，ダニ間の交叉反応性が疑われたアナフィラキシーの２症例

DOI 被引用文献2件

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タイトル別名
  • Two Cases of Anaphylaxis Presumably Provoked by Cross-reactivity among Crustaceans, Mollusks, Anisakis, Roundworms, Cockroaches, and House-dust Mites.

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説明

We report here two cases of anaphylaxis, of which we suspected tropomyosin-related protein as a causal antigen. Case 1; A 26-year-old man developed anaphylaxis after taking chikuwa which is usually made of mashed cod. He had also experienced dyspnea after taking shrimp or crab since childhood. Case 2; A 60-year-old woman developed generalized flush and hypotension with anaphylaxis after taking octopus and squid. Radioallergosorbent test for Ig E revealed that both patients had specific Ig E for shrimp, crab, squid, cockroach, roundworm, anisakis, and house-dust mite. By skin test, both patients strongly responded for shrimp, crab, squid, and anisakis. Immunoblot analysis revealed that both of patient sera reacted with 34kd anisakis antigen. Based on these findings and literatures, we speculate that there is a possible cross-reactivity among antigens in these creatures which are known to have an identical allergen, tropomyosin.

収録刊行物

  • 皮膚

    皮膚 43 (1), 67-73, 2001

    日本皮膚科学会大阪地方会

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