Medullary Thyroid Carcinoma, Multiple Mucosal Neuroma and Marfanoid Habitus in a boy aged 6 years : Syndrome MEN, Type III
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- Tsukuda Kunio
- Department of Surgery, Yamaguchi Central Hospital
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- Nomura Shigeru
- Department of Surgery, Yamaguchi Central Hospital
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- Harada Eiji
- Department of Surgery, Yamaguchi Central Hospital
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- Tanaka Kimiro
- Department of Surgery, Yamaguchi Central Hospital
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- Nakayasu Kiyoshi
- Department of Surgery, Yamaguchi Central Hospital
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- Ofuji Kaoru
- Department of Surgery, Yamaguchi Central Hospital
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- Kondo Naotsugu
- Department of Surgery, Yamaguchi Central Hospital
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- Hongo Hiroshi
- Department of Surgery, Yamaguchi Central Hospital
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- Hirayu Hideji
- Department of Internal Medicine, Yamaguchi Central Hospital
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- Kamei Toshiaki
- Department of Pathology, Yamaguchi Central Hospital
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- Nakamura Hidenori
- The First Department of Pathology, Yamaguchi University School of Medicine
Bibliographic Information
- Other Title
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- 小児の Multiple Endocrine Neoplasia,Type 3 の1例
- ショウニ ノ Multiple Endocrine Neoplasia Typ
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Abstract
MEN, type III is an extremely rare syndrome. Only six cases have been reported in Japan. Recently we experienced a case with medullary thyroid carcinoma, multiple mucosal neuroma and Marfanoid habitus in childhood, which is the youngest case in Japanese literatures. A 6-year-old boy was admitted with a complaint of left cervical tumors. "Bumpy" lips, Marfanoid habitus and whitish papillary lesions on the tongue tip which was histologically proved plexiform neuroma were characteristic. Megacolon, polyps of colon, diverticulosis coli and medullated corneal nerves were also detected. Under the diagnosis of thyroid cancer, resection of the left lobe of the thyroid with bilateral modified radical neck dissection was carried out. Postoperative calcitonin level remained high (5,674 pg/ml, indicating incomplete removal of the metastatic medullary thyroid carcinoma in the anterior mediastinum. External radiotherapy by 60^Co was performed postoperatively. A series of endocrinological examination failed to find a pheochromocytoma. A careful study of the family history gave a negative result.
Journal
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- Journal of the Japanese Society of Pediatric Surgeons
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Journal of the Japanese Society of Pediatric Surgeons 18 (6), 1181-1188, 1982
The Japanese Society of Pediatric Surgeons
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Details 詳細情報について
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- CRID
- 1390001204805301504
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- NII Article ID
- 110002081248
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- NII Book ID
- AN00192281
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- ISSN
- 21874247
- 0288609X
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- NDL BIB ID
- 2617006
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed