Testicular Yolk Sac Tumor in Children : Report of Six Cases

DOI Web Site 20 References
  • Sugiyama Akihide
    Division of Pediatric Surgery, Children's Medical Center, Showa University Northern Yokohama Hospital
  • Gomi Akira
    Division of Pediatric Surgery, Children's Medical Center, Showa University Northern Yokohama Hospital
  • Ohashi Yusuke
    Division of Pediatric Surgery, Children's Medical Center, Showa University Northern Yokohama Hospital
  • Kawano Sinya
    Department of Surgery, Showa University Fujigaoka Hospital
  • Chiba Masahiro
    Department of Surgery, Showa University Fujigaoka Hospital
  • Sanada Yutaka
    Department of Surgery, Showa University Fujigaoka Hospital
  • Yatsuzuka Masashi
    Department of Pediatric Surgery, Showa University Hospital
  • Toki Akira
    Department of Pediatric Surgery, Showa University Hospital
  • Yamada Kouichirou
    Department of Pediatrics, Showa University Fujigaoka Hospital

Bibliographic Information

Other Title
  • 小児精巣yolk sac tumor 6例の治療経験
  • 症例報告 小児精巣yolk sac tumor 6例の治療経験
  • ショウレイ ホウコク ショウニセイソウ yolk sac tumor 6レイ ノ チリョウ ケイケン

Search this article

Abstract

We describe our experience with 6 children with testicular yolk sac tumor (YST) treated in the past 12 years. The age of patients ranged from 4 months to 27 months with an average of 15 months. Hydrocele testis occurred in 2 cases. In 4 cases the tumor was located in the right testis, and in the other 2 cases in the left. All patients underwent high orchiectomy as the initial treatment. Four patients presented with Stage I disease and the remainder presented with Stage III 0 or Stage IIIB disease. All patients were free of evidence of disease after a mean follow-up period of 4.8 years. Three patients received platinum-based combination chemotherapy. In conclusion, high orchiectomy alone seems adequate for Stage I testicular YST. Post-operative chemoprevention is likely to be required, if tumor cell invasion into vessels is histologically revealed in the resected specimen. Serial monitoring of the AFP degradation curve plays an important role in the management of post-operative testicular YST. Patients with metastatic disease or recurrent disease can be treated successfully with platinumbased combination chemotherapy.

Journal

References(20)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top