A Case of Gastrointestinal Stromal Tumor of Rectum with Immunohistochemically Positive for C-kit
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- KAWANO Kazuaki
- Department of Surgery, Yamaguchi Rosai Hospital
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- KATOH Tomoe
- Department of Surgery, Yamaguchi Rosai Hospital
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- YAGI Takaharu
- Department of Surgery, Yamaguchi Rosai Hospital
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- HIRATA Ken
- Department of Surgery, Yamaguchi Rosai Hospital
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- HAYASHI Masataro
- Department of Surgery, Yamaguchi Rosai Hospital
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- SEYAMA Atsushi
- Department of Surgery, Yamaguchi Rosai Hospital
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- OGA Atsunori
- Dept of Pathology II. and. Molecular Science & Applied Medicine, Yamaguchi University School of Medicine
Bibliographic Information
- Other Title
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- 直腸原発c‐kit陽性gastrointestinal stromal tumor (GIST)の1例
- チョクチョウ ゲンパツ c-kit ヨウセイ gastrointestinal stromal tumor GIST ノ 1レイ
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Abstract
A 78-year-old man consulted a nearby clinic because of melena, and was admitted to the hospital. Diagnostic imaging revealed a submucosal tumor with central ulceration in the left wall of the lower rectum. A Miles' operation was performed following the diagnosis and the tumor was 47×40×35mm in size. Histological examination of the resected specimen showed the tumor to be composed of spindle shaped cells with a few mitosis. Tumor cells were positive for c-kit and CD34, negative for α-SMA and S-100 by immunohistochemical examination. We diagnosed this tumor as gastrointestinal stromal tumor (GIST), uncomitted type, malignant. He has been well for 2 years 7 months after operation without evidence of recurrence. GIST of the rectum with immunohistochemically positive for c-kit is rare with only 18 reported cases in the Japanese literature. This immunohistochemical evaluation with c-kit has been essential for the diagnosis of GIST.
Journal
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- Yamaguchi Medical Journal
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Yamaguchi Medical Journal 53 (2), 109-114, 2004
Yamaguchi University Medical Association
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Details 詳細情報について
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- CRID
- 1390001204835492480
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- NII Article ID
- 110002773910
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- NII Book ID
- AN00243156
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- ISSN
- 18804462
- 05131731
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- Text Lang
- ja
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- Data Source
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- JaLC
- IRDB
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed