Newly Found Pulmonary Pathophysiology from Automated Breath-Hold Perfusion-SPECT-CT Fusion Image

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  • 自動作成息止め肺血流ＳＰＥＣＴ－ＣＴ融合像から得られた肺病態の新知見
  • ジドウ サクセイ イキドメ ハイ ケツリュウ SPECT-CT ユウゴウゾウ カラ エラレタ ハイ ビョウタイ ノ シンチケン ミニ レビュー : コニシショウ ジュショウシャ
  • 小西賞受賞者 自動作成息止め肺血流SPECT-CT融合像から得られた肺病態の新知見
  • コニシショウ ジュショウシャ ジドウ サクセイ ソク ヤメ ハイ ケツリュウ SPECT CT ユウゴウゾウ カラ エラレタ ハイビョウタイ ノ シン チケン

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Abstract

Pulmonary perfusion SPECT-CT fusion image largely contributes to objective and detailed correlation between lung morphologic and perfusion impairment in various lung diseases. However, traditional perfusion SPECT obtained during rest breathing usually shows a significant mis-registration on fusion image with conventional CT obtained during deep-inspiratory phase. There are also other adverse effects caused by respiratory lung motion such as blurring or smearing of small perfusion defects. To resolve these disadvantages of traditional perfusion SPECT, an innovative method of deep-inspiratory breath-hold (DIBrH) SPECT scan is developed in the Nuclear Medicine Institute of Yamaguchi University Hospital. This review article briefly describes the new findings of pulmonary pathophysiology which has been reveled by detailed lung morphologic-perfusion correlation on automated reliable DIBrH perfusion SPECT-CT fusion image.

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