耳鳴のイオン浸透法によるステロイド療法と歪成分耳音響放射

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  • Iontophoresis of Dexamethasone for Tinnitus and DPOAE(Preliminary Report).

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The effects of iontophoresis by dexamethasone and lidocain for tinnitus were evaluated with distortion product otoacoustic emissions (DPOAE). Volunteers with normal hearing and patients with tinnitus were treated by iontophoresis with a mixture of 0.1% dexamethasone and 4% lidocain solution (4:1). The positive ear pole was used, and a direct current flow of 0.5mA was applied for 10 minutes. Experimental studies with physiological saline were performed in normal subjects.<br>After the treatments, average DP levels were significantly increased at 1001Hz (F2) in the effective cases (especially acute tinnitus with low-tone hearing loss), slightly decreased in the non-effective cases, and unchanged in the normal subjects. The average DP change values between effective and non-effective cases were significantly different at 1001Hz (F2). The average DP levels for all the groups treated with iontophoresis, significantly decreased at high tone.<br>The author suggested that the increase of the DP levels at middle tone for the effective cases were due to the therapeutic effects of dexamethasone and the decrease at high tone for all the treated cases were due to the effects of electrical current. The auther speculated that dexamethasone negative ions infiltrate into the ear drum with lidocain positive ions and water by electroosmosis, infiltrate into the cochlea through the round window, and improve cochlear function. These treatments were painless without side effect.

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