EXPERIMENTAL STUDY OF EFFECTS OF ALLOXAN ON BLOOD AQUEOUS BARRIER IN RABBITS

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  • Yoshida Makoto
    Department of Ophthalmology, School of Medicine, Showa University

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  • 家兎眼血液房水棚に及ぼすAlloxanの影響
  • カトガン ケツエキ ボウスイダナ ニ オヨボス alloxan ノ エイキョウ

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Using glucose as the diffusive substance, vitamin C as the active transferable substance, effects of alloxan on blood aqueous barrier of albino rabbits followed by the time were measured.<BR>1) I found in injection of alloxan that the sugar levels of aqueous humor were increased in proportion to the sugar levels of blood in comparative hypoglycemia, but the former did not increase in proportion to the latter in hyperglycemia more than 400 mg/dl. It was not observed only in this experiment whether the passive transferable functions were damaged or not by alloxan.<BR>2) There were no remarkable damages on the active transferable function of vitamin C in injection of alloxan (100 mg/kg or 200 mg/kg)<BR>3) It might be that the injection of 100 mg/kg of alloxan did not influence the penetration of glucose and vitamin C into the lens capsel.

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