切除胃における組織肥胖細胞の病理組織学的研究

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タイトル別名
  • HISTOPATHOLOGICAL STUDIES ON THE TISSUE MAST CELLS IN THE RESECTED STOMACHS
  • セツジョ イ ニ オケル ソシキヒハンサイボウ ノ ビョウリ ソシキガクテキ ケンキュウ

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A lot of sections of the gastric walls for microscopic examination were made from 53 resected stomachs consisting of 5 cases of so-called chronic gastritis, 16 cases of chronic gastric ulcer and 36 cases of gastric cancer. Mast cell counts were done in the mucosa, submucosa, muscularis and seresa layers by the binocular microscope (400 X high power) . The results obtained were as follows.<BR>1. Many mast cells were constantly observed in the layer of the tunica propria in case of so-called chronic gastritis. And then there are relatively many mast cells in the layer of the submucosa however few mast cells in the layers of muscularis, muscularis mucosae, and serosa. There are constant disributions of mast cells beneath the layer of the muscularis mucosae. In each cases there are remarkable differences in counts of mast cells.<BR>2. In the normal gastric wall, almost same distributions of mast cells in the so-called chronic gastritis were easily imagined.<BR>3. On the distributions of mast cells in chronic gastric ulcer there are many mast cells in fibrous area of the callus calosum. On the contrary, fewer mast cells wre observed in the area of loose connective tissue near the surface of the ulcer. Around the callus calosum increased mast cells were noticed in the layer of submucosa and muscularis. In such cases even in the layer of the serosa there are many mast cells.<BR>4. On the distribttions of the tissue mast cells in cancer of the stomach there are many differnces in cases. Tissue mast cells seem to increase in number in the stroma around the tumor than in the tumor itself. From view of the histological pattern tissue mast cells increase in the scirrhous pattern more than medullary pattern.<BR>5. In the ulcer or stroma metachromasia by Squartini increasing et al in the part of the fibrous tissue with metachromasia there are many mast cells in number. This suggests that tissue mast cells take part in reformation with fibrosis greatly.

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