A Case of Primary Carcinoid Tumor of the Breast.

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  • 乳腺カルチノイドの１例

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Primary carcinoid tumor of the breast is quite rare, and there have been only 31 operated cases in the Japanese literature. A 45-year-old woman had a palpable tumor 1.5×1.0cm in size in the A region of the left breast. Ultrasound examination showed an irregular shaped low echoic tumor, and in the left anterior chest wall, a CT scan demonstrated a round shaped tumor which was separated from mammary gland tissues. Excisional biopsy was performed. Hematoxylin and eosin (HE) stains showed a carcinoid like appearance, because the tumor was composed of small cells arranged in solid nests or in a trabecular pattern. Grimelius technique demonstrated numerous argyrophillic granules in the cytoplasm of many tumor cells, and chromogranin A stain was positive. From these figures of the tumor cells, carcinoid tumor was diagnosed. We had still difficulty in differential diagnosis between primary carcinoid tumor of the breast and metastatic carcinoid tumor to the breast. Wide excision was performed. Histologically foreign body granuloma was seen and atrophic mammary gland tissues were seen in the vicinity of the granuloma. At last we diagnosed the case as primary carcinoid tumor of the breast.

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