A CASE OF GASTROINTESTINAL STROMAL TUMOR OF DUODENUM SURVIVING OVER 19 YEARS BY REPEATED RESECTIONS

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  • 肝・腹膜・肺再発に対し４回の切除術を行い１９年生存中の十二指腸原発ＧＩＳＴの１例

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Abstract

A 75-year-old woman with a pelvic tumor measuring 13 cm in diameter, which was found by follow-up abdominal CT after extended right lobectomy and partial lateral segmentectomy for metachronous liver metastases from leiomyosarcoma originated duodenum, was referred to our hospital. Chest CT also showed a solitary nodule in left lower lobe measuring 1.5 cm. Resections of pelvic tumor and a small peritoneal nodule following left lower lobectomy of lung were performed subsequently. Pathological examination revealed that all of the resected tumors consisted of spindle-shaped tumor cells which were positive for c-kit immunohistochemically. Thus, it was diagnosed as metastases of GIST. Aggressive resection of metastases from GIST, especially in cases with a long disease-free interval between initial resection and recurrences might contribute to prolonged prognosis.

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