A CASE OF POSTOPERATIVE LIVER METASTASIS FROM MEDULLARY CARCINOMA OF THYROID TREATED WITH CHEMOEMBOLIZATION

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  • TAKIZAWA Hiromitsu
    Department of Oncological and Regenerative Surgery, University of Tokushima, School of Medicine
  • NAKANO Kiichiro
    Department of Oncological and Regenerative Surgery, University of Tokushima, School of Medicine
  • KENZAKI Koichiro
    Department of Oncological and Regenerative Surgery, University of Tokushima, School of Medicine
  • KOMAKI Kansei
    Department of Oncological and Regenerative Surgery, University of Tokushima, School of Medicine
  • MORIMOTO Tadaoki
    University of Tokushima, School of Health Science
  • TANGOKU Akira
    Department of Oncological and Regenerative Surgery, University of Tokushima, School of Medicine

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  • 甲状腺髄様癌術後肝転移に対し肝動脈化学塞栓療法が有効であった１例

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We report a case of postoperative liver metastasis from medullary carcinoma of thyroid treated with chemoembolization which resulted in stable values of tumor markers for 2 yeas after the treatment.<br> The female patient underwent total thyroidectomy and lymphadenectomy (D3a) for medullary carcinoma of thyroid (pT2bN1bM0) of the age of 14. The values of serum CEA and calcitonin gradually increased at the age of 17, but various imaging examinations showed no recurrence or metastatic lesions. Eight years after the operation when she was 22, enhanced computed tomographic scan showed multiple metastatic lesions with the diameter of less than 1.5cm, which were enhanced in the early phase, of the liver. The value of serum CEA was 852.9ng/ml, and calcitonin was 12100pg/ml. We performed chemoembolization 3 times for these lesions. Though 2 years have elapsed afterward, no changes in the size or shape of the hepatic masses have been observed and the values of serum CEA and calcitonin remains relatively low (CEA: 577.5ng/ml and calcitonin: 6400pg/ml).

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