A CASE OF LARGE CELL NEUROENDOCRINE CARCINOMA ORIGINATING FROM THE BREAST
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- MOROHASHI Satoko
- Department of Surgery, Hirosaki University School of Medicine
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- MOROHASHI Hajime
- Department of Surgery, Hirosaki University School of Medicine
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- AKASAKA Harue
- Department of Surgery, Hirosaki University School of Medicine
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- NISHIMURA Akimasa
- Department of Surgery, Hirosaki University School of Medicine
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- ODAGIRI Hiroki
- Department of Surgery, Hirosaki University School of Medicine
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- HAKAMADA Kenichi
- Department of Surgery, Hirosaki University School of Medicine
Bibliographic Information
- Other Title
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- 乳腺原発large cell neuroendocrine carcinomaの1例
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Abstract
This paper deals with a 57-year-old woman who was found having a right breast tumor during exploration for carcinoma of the uterine body. CT revealed synchronous multiple hepatic metastases as well. The patient was referred to our department and underwent right partial mastectomy. Histopathological studies showed that the tumor cells were large with prominent atypical nuclei, and immunohistochemically neuroendocrine markers were positive. Thus large cell neuroendocrine carcinoma (LCNEC) was diagnosed. The liver metastases were initially considered to be derived from carcinoma of the uterine body, however, total hysterectomy and bilateral adnexectomy for uterine body carcinoma disclosed that the disease was in postoperative clinical stage Ib. Accordingly hepatic metastases were considered to be due to breast LCNEC rather than due to uterine body carcinoma. The patient received chemotherapy at our department, but died about 10 months after the mastectomy.<BR>Few cases of breast LCNEC have been reported in this country, so that we have to accumulate clinical cases to evaluate the therapeutic outcomes and prognosis.
Journal
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- Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
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Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 70 (10), 2955-2959, 2009
Japan Surgical Association
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Details 詳細情報について
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- CRID
- 1390001204849873536
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- NII Article ID
- 130004517151
- 10026338261
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- NII Book ID
- AA11189709
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- ISSN
- 18825133
- 13452843
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed