食道原発verrucous carcinomaの1切除例

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  • A CASE OF VERRUCOUS CARCINOMA OF THE ESOPHAGUS WITH SUCCESSFUL RESECTION

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A patient, 72-year-old male, came to the hospital with the chief complaints of hematemesis, melena and anorexia. On endoscopic examination a irregular protruded lesion with verrucous appearance was detected on the lower esophagus at 35cm from incisors down to the cardia. Endoscopic biopsies revealed squamous cell carcinoma and esophago-gastrectomy was performed with the diagnosis of esophageal cancer. Operative procedures included distal esophagectomy, proximal gastrectomy, splenectomy and D2 lymph node dissection. Macroscopic findings of the resected specimen showed a cauliflower-like appearance with irregular surface, measuring 8.0×7.0cm. Histological examination revealed a well-differentiated squamous cell carcinoma with papillary proliferation of epithelium. From these findings, the pathologic diagnosis was verrucous carcinoma of the esophagus. The histological stage was pT3, pN0, M0, ly0, v0, pPM0, pDM0, pEM0. and stage II. No signs of recurrence have been observed for two years after the operation. Verrucous carcinoma of the esophagus is extremely rare, and only 19 cases have been reported until today. The author discussed the clinical and histopathological characteristics of esophageal verrucous carcinoma reviewing some published literatures.

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