腹膜原発漿液性乳頭状癌の1例

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  • A CASE OF PERITONEAL SEROUS PAPILLARY CARCINOMA

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A 64-year-old woman underwent an exploratory laparotomy under a diagnosis of peritonitis carcinomatosa of unknown origin in July 1991. There was gross ascites in the abdominal cavity, and a tumor was found at the transverse mesocolon and on the surface of rectum. The histologic finding of biopsied specimen of the tumor was adenocarcinoma.<br> No primary malignant tumor was detected on any organs by a whole body imaging. She was diagnosised as peritonitis carcinomatosa of unkown origin, and carboplatin-based chemotherapy was started. After the treatment the volume of ascitis decreased, and the tumor remarkably diminished in size.<br> In June 1997, the tumor invaded the transverse colon, and a partial transverse colectomy was performed. Histologic finding of the tumor was papillary adenocacinoma. From these clinical findings, we diagnosed this case as peritoneal serous papillary carcinoma (PSPC).<br> PSPC is considered to be a disease originating from the peritoneum, and is an uncommon entity. Here we present the patient with PSPC who had good response to chemotherapy with surgical operation, and has been alive for eight years after the therapy.

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