A Case Report of Pathologic Complete Response with Neoadjuvant Chemo (UFT+UZEL) -Radiation (IMRT) for Locally Advanced Rectal Cancer Invading other Organs
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- NISHIGAMI Kohei
- Department of Gastrointestinal Surgery, Hokuto Hospital
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- TARAO Hisashi
- Department of Gastrointestinal Surgery, Hokuto Hospital
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- YAMAGUCHI Tomohito
- Department of Gastrointestinal Surgery, Hokuto Hospital
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- YAMAGUCHI Kiyotaka
- Department of Gastrointestinal Surgery, Hokuto Hospital
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- KAWAMI Hiroyuki
- Department of Gastrointestinal Surgery, Hokuto Hospital
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- TANAKA Takashi
- Sentinel Clinic
Bibliographic Information
- Other Title
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- 強度変調放射線治療を用いた術前CRTによりpCRが得られた局所進行直腸癌の1例
- 症例 強度変調放射線治療を用いた術前CRTによりpCRが得られた局所進行直腸癌の1例
- ショウレイ キョウド ヘンチョウ ホウシャセン チリョウ オ モチイタ ジュツゼン CRT ニ ヨリ pCR ガ エラレタ キョクショ シンコウ チョクチョウ ガン ノ 1レイ
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Abstract
A 65-year-old man presented to a local hospital because of diarrhea and abdominal pain. Following colonoscopy and abdominal CT, rectal cancer, ileus and a retoroperitoneal abscess were diagnosed. He was referred to our hospital. We performed percutaneous dranage for the retroperitonial abscess, followed by only transient colostomy because the rectal cancer had invaded the bladder and the left wall of pelvis, and his general condition was poor due to the abscess and ileus. A tolal of 40 Grey IMRT (intensity-modulated radiation therapy) with UFT + UZEL chemotherapy for 28 days was given. After the therapy, CT, FDG-PET and colonoscopy revealed remarkable shrinkage of the tumor. High anterior resection of the rectum with D3 lymphadenectomy and partial resection of the bladder were then performed. Histopathological examination showed complete regression of the tumor, rated as Grade 3, pathologic complete response (pCR).
Journal
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- Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
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Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 74 (7), 1962-1967, 2013
Japan Surgical Association
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Details 詳細情報について
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- CRID
- 1390001204850657920
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- NII Article ID
- 10031203048
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- NII Book ID
- AA11189709
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- ISSN
- 18825133
- 13452843
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- NDL BIB ID
- 030743915
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed