A case of neurofibromatosis type 1 associated with neuroendocrine tumor and GIST in the duodenum

NAKAMURA Masanori, YAMADA Nobuya, AMANO Ryosuke, KIMURA Kenjiro, HIRAKAWA Kosei

doi:10.3919/jjsa.74.942

Bibliographic Information

Other Title

十二指腸に神経内分泌腫瘍とGISTを併発した神経線維腫症1型の1例
症例十二指腸に神経内分泌腫瘍とGISTを併発した神経線維腫症1型の1例
ショウレイジュウニシチョウニシンケイナイブンピシュヨウト GIST オヘイハツシタシンケイセンイシュショウ 1ガタノ 1レイ

Search this article

Abstract

A 42-year-old man with neurofibromatosis type 1 (NF1) who visited a hospital because of tarry stool in March 2010 was referred to our hospital because a duodenal tumor was detected by upper gastrointestinal endoscopy. Abdominal CT scan revealed a 50 × 50 × 25 mm tumor from the second to the third part of duodenum. Upper gastrointestinal endoscopy and EUS showed a 21 × 16 mm submucosal tumor with a central depression in the vicinity of the papilla of Vater at the second part of duodenum, and it was proved to be neuroendocrine tumor (NET) by a biopsy. Another submucosal tumor 51 × 31 mm in diameter was present in the third part of duodenum. Pancreaticoduodenectomy was performed in May. The histopathology resulted in NET and gastrointestinal stromal tumor (GIST). The postoperative course was uneventful. The patient was discharged from our hospital on the 19^th postoperative day and has been free from recurrence as of 2 years and 8 months after the operation.<BR>Recently clinical cases of NF1 associated with either NET or GIST have sometimes been reported, however, there are few cases of NF1 associated with the both diseases concomitantly. We thus report this case of NF1 with NET and GIST of the duodenum, together with some bibliographic comments.

Journal

Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)

Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 74 (4), 942-946, 2013

Japan Surgical Association

Keywords

Details 詳細情報について

Export