A Case of Pneumatosis Cystoides Intestinalis with Hepatic Portal Venous Gas Induced by α-Glucosidase Inhibitor

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  • 門脈ガスを伴ったα-グルコシダーゼ阻害薬による腸管嚢腫様気腫症の1例
  • 症例 門脈ガスを伴ったα-グルコシダーゼ阻害薬による腸管囊腫様気腫症の1例
  • ショウレイ モンミャク ガス オ トモナッタ a-グルコシダーゼ ソガイヤク ニ ヨル チョウカンノウ シュ ヨウキシュショウ ノ 1レイ
  • A Case of Pneumatosis Cystoides Intestinalis with Hepatic Portal Venous Gas Induced by ^|^alpha;-Glucosidase Inhibitor

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Abstract

A 74-year-old woman was brought into our hospital because of abdominal distension after an enema administration. Abdominal CT scan showed free air, hepatic portal venous gas, and pneumatosis cystoides intestinalis in the wall of the small intestine. There were no apparent findings suggestive of intestinal necrosis and gastrointestinal perforation. The patient's condition improved through conservative therapy including withdrawal of an α-glucosidase inhibitor for diabetes. Recentely pneumatosis cystoides intestinalis caused by α-glucosidase inhibitors has sometimes been reported. We consider that an α-glucosidase inhibitor might induce pneumatosis cystoides intestinalis in this case. Abrupt elevation of the inner pressure in the intestine due to the enema might cause rupture of emphysema, transference of gas into the vessel, and resultant free air and hepatic portal venous gas.

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