A Case of Mediastinal Neurofibroma of the Vagus Nerve Mimicking Mediastinal Lymph Node

  • DEGUCHI Hiroyuki
    Department of General Thoracic Surgery, Iwate Medical University
  • TOMOYASU Makoto
    Department of General Thoracic Surgery, Iwate Medical University
  • SHIGEEDA Wataru
    Department of General Thoracic Surgery, Iwate Medical University
  • KANEKO Yuka
    Department of General Thoracic Surgery, Iwate Medical University
  • MUE Yoshiharu
    Department of Molecular Diagnostic Pathology, Iwate Medical University
  • TANITA Tatsuo
    Department of General Thoracic Surgery, Iwate Medical University

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Other Title
  • 縦隔リンパ節と鑑別を要した迷走神経由来神経線維腫の1例
  • 症例 縦隔リンパ節と鑑別を要した迷走神経由来神経線維腫の1例
  • ショウレイ ジュウカク リンパセツ ト カンベツ オ ヨウシタ メイソウ シンケイ ユライ シンケイ センイ シュ ノ 1レイ

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A 76-year-old man was referred to our hospital because of an abnormal shadow on a chest X-ray film at a medical checkup. Chest CT scan showed a mass 45 mm in diameter in the right upper lobe of the lung, PET-CT showed a maximum SUV of 13.5 in the same area and we suspected primary lung cancer. Mediastinal lymph node was not diagnosed as metastasis because the diameter was less than 1cm in shorter axis on CT and fluorodeoxyglucose (FDG) uptake was low on PET. We performed lobectomy of the right upper lobe and the intraoperative frozen section histopathological diagnosis was reported to be carcinoma. We shifted to lymph node dissection and found a white tumor which occupied the superior mediastinum and originated from the vagus nerve. We resected the mediastinal tumor. The pathological diagnosis of the lung tumor was pleomorphic carcinoma and that of the nourogenic tumor was neurofibroma. He had café au lait spots and had undergone the resection of a neurofibroma in the leg. He was diagnosed with neurofibromatosis type 1.

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