A Case of Rapidly Progressive and Disseminated Meningeal Carcinomatosis from Breast Cancer

DOI Web Site Web Site 6 References
  • NOMOTO Yuki
    Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Hospital
  • KIJIMA Yuko
    Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Hospital
  • SHINDEN Yoshiaki
    Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Hospital
  • HIRATA Munetsugu
    Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Hospital
  • YOSHINAKA Heiji
    Department of Breast Surgery, Kagoshima City Hospital
  • NATSUGOE Shoji
    Department of Digestive Surgery, Breast and Thyroid Surgery, Kagoshima University Hospital

Bibliographic Information

Other Title
  • 急速に進行した乳癌髄膜播種の1例
  • 症例 急速に進行した乳癌髄膜播種の1例
  • ショウレイ キュウソク ニ シンコウ シタ ニュウガン ズイマク ハシュ ノ 1レイ

Search this article

Abstract

A 57-year-old woman was diagnosed with left breast cancer in March 2011 and a mastectomy with axillary and infraclavicular lymph node dissection was performed (pT2N3aM0 stage IIIC). Postoperative adjuvant therapy consisting of four courses of cyclophosphamide plus epirubicin was administered starting in April 2011, and then four courses of paclitaxel were administered starting in July 2011. In January 2012, her tumor marker levels (CEA, CA15-3) were elevated and multiple liver metastases were detected. We administered six more courses of cyclophosphamide plus epirubicin. Her tumor marker levels (CEA, CA15-3) decreased and the liver metastases shrank.<BR>Starting in May, she complained of appetite loss and her performance status rapidly decreased. We could not detect any abnormal findings on brain computed tomography. Twenty days after the appearance of symptoms, brain magnetic resonance imaging revealed leptomeningeal enhancement and malignant cells were collected from the cerebrospinal fluid. She was diagnosed with meningeal carcinomatosis from breast cancer. Herein, we report a case of meningeal carcinomatosis from breast cancer which progressed rapidly, with review of literature.

Journal

References(6)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top