書誌事項
- タイトル別名
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- Incidental mesangial IgA deposition in minimal change nephrotic syndrome (MCNS).
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説明
The frequency of incidental mesangial IgA deposition and its clinicopathological features were investigated in patients with minimal change nephrotic syndrome (MCNS) . Mesangial IgA deposition was present in 15/63 patients (23.8 %), and co-deposition of IgA and C3 was present in 10/63 patients (15.9 %). The serum IgA concentration was significantly higher in IgA (+) patients than in IgA (-) patients (341±79 mg/dl vs. 252±99 mg/dl, p=0.034) . The urinary red blood cell count tended to be higher in IgA (+) patients than in IgA (-) patients (12.8±24.9 vs. 5.0±7.9 counts/HPF, p=0.58) . Histologically, no significant differences were observed between IgA (+) and IgA (-) patients. After steroid treatment, 14 patients with mesangial IgA deposition showed complete remission and one patient had persistent proteinuria . The microhematuria also disappeared after steroid treatment in 13/15 patients (86 .7 %), although it reappeared in 6/13 patients (46 %) during reduction of steroid administration. The present study indicated that the incidental mesangial IgA deposition was frequently observed in MCNS patients (23 .8 %) . The phenomenon of mesangial IgA deposition was related to the higher concentration of serum IgA . However, no influence of mesangial IgA doposition in MCNS patients was found on the post treatment amount of proteinuria, renal function and clinical outcome of MCNS.
収録刊行物
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- 日本腎臓学会誌
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日本腎臓学会誌 45 (7), 681-688, 2003
社団法人 日本腎臓学会
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詳細情報 詳細情報について
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- CRID
- 1390001204858676096
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- NII論文ID
- 130004170639
- 50000332365
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- NII書誌ID
- AN10131749
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- ISSN
- 18840728
- 03852385
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- PubMed
- 14631763
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- 本文言語コード
- ja
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
