HISTOCHEMICAL STUDY OF NON-SPECIFIC ESTERASE ACTIVITY IN THE LIVER, KIDNEY AND SMALL INTESTINE FROM NINE DIFFERENT MAMMALIAN SPECIES

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Non-specific esterase in the liver, kidney and small intestine of nine different mammalian species (monkey, dog, cat, mink, rabbit, hamster, guinea pig, rat and mouse) was studied by light and electron microscopy, with thiolacetic acid as a substrate. In the liver and kidney, strong activity was observed in all of the species except in the mink liver. Both smooth and rough endoplasmic reticulum, including the nuclear envelope, were intensely reactive. A marked difference of species was shown in the small intestine, for an intense reaction occurred in the apical region of epithelial cells in all species except the dog, cat and mink. These results were in close agreement with those obtained from a biochemical assay.

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