Hypogammaglobulinemia with Nodular Lymphoid Hyperplasia of the Small Intestine
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- ARIKAWA Kazumi
- The Department of Medicine, School of Medicine, Keio University
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- Asakura Hitoshi
- The Department of Medicine, School of Medicine, Keio University
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- ICHIKAWA Yoichi
- The Department of Medicine, School of Medicine, Keio University
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- ABE Tohru
- The Department of Medicine, School of Medicine, Keio University
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- HOMMA Mitsuo
- The Department of Medicine, School of Medicine, Keio University
Bibliographic Information
- Other Title
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- Hypogammaglobulinemia with Nodular Lymp
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Abstract
A case of hypogammaglobulinemia with nodular lymphoid hyperplasia of the small intestine was presented with its immunological analysis. A peroral biopsy of the proximal jejunum demonstrated enlarged lymphoid follicles with large germinal centers. Only a few plasma cells were observed. Serum IgG and IgM were markedly reduced, IgA, IgD and IgM could not be traced. Secretory IgA was absent in saliva, while normal amount of secretory component was present. Peripheral B-lymphocytes (B-cells) enumerated by surface immunoglobulin receptors were rather increased while B-cells determined by C3 receptors were markedly decreased. Peripheral T-lymphocytes measured by sheep red blood cell rosette formation were increased in number, but their function was depressed as judged by the response to PHA. The pathogenesis of this disorder was discussed, reviewing 27 cases of this syndrome so far reported.
Journal
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- Japanese Journal of Medicine
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Japanese Journal of Medicine 16 (3), 251-259, 1977
The Japanese Society of Internal Medicine
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Keywords
Details 詳細情報について
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- CRID
- 1390001204867286912
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- NII Article ID
- 130003513513
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- NII Book ID
- AA00691133
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- ISSN
- 1881123X
- 00215120
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- NDL BIB ID
- 1833419
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed