Fatal Hyperammonemia in a Patient with Systemic Lupus Erythematosus.
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- ICHIKAWA Haruo
- The Department of Medicine III, Okayama University Medical School
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- AMANO Tetsuki
- The Department of Medicine III, Okayama University Medical School
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- KAWABATA Kenji
- The Department of Medicine III, Okayama University Medical School
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- KUSHIRO Masahiko
- The Department of Medicine III, Okayama University Medical School
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- WADA Jun
- The Department of Medicine III, Okayama University Medical School
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- NAGAKE Yoshio
- The Department of Medicine III, Okayama University Medical School
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- MAKING Hirofumi
- The Department of Medicine III, Okayama University Medical School
書誌事項
- タイトル別名
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- Fatal Hyperammonemia in a Patient with
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We treated a 31-year-old woman with systemic lupus erythematosus, renal failure with nephrotic syndrome, and a long-standing seizure disorder, who developed severe hyperammonemia with a fatal outcome. Blood chemistry examination did not indicate liver disease, and amino acid concentrations did not suggest a defect in the urea cycle. Discontinuation of anticonvulsant treatment with valproic acid (VPA) failed to bring about improvement. We speculated that hyperanimonemia in this case was induced by VPA, and the existence of other underlying factors, including the administration of aspirin and cimetidine, hypoalbuminemia, and renal failure might elevate the concentration of the serum free fraction of VPA.<br>(Internal Medicine 37: 700-703, 1998)
収録刊行物
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- Internal Medicine
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Internal Medicine 37 (8), 700-703, 1998
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390001204868192896
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- NII論文ID
- 10009507685
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- NII書誌ID
- AA10827774
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- COI
- 1:STN:280:DyaK1cvhs12nsw%3D%3D
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 4555845
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- PubMed
- 9745859
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可