Treatment of Essential and Parkinsonian Tremor with Nipradilol.
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- YOSHII Fumihito
- The Department of Neurology, Tokai University School of Medicine
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- SHINOHARA Yukito
- The Department of Neurology, Tokai University School of Medicine
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- TAKEOKA Tsuneyuki
- The Department of Neurology, Tokai University Tokyo Hospital
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- KITAGAWA Yasuhisa
- The Department of Neurology, Tokai University Oiso Hospital
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- AKIYAMA Katsunori
- The Department of Neurology, Hiratsuka City Hospital
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- YAZAKI Koji
- The Department of Neurology, Yamato City Hospital
書誌事項
- タイトル別名
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- Treatment of Essential and Parkinsonian
この論文をさがす
説明
Nipradilol is a new type of β-blocker which possesses nitroglycerin-like vasodilating action in addition to β-blocking action. We investigated the efficacy and safety of nipradilol for treating tremor in 20 patients with essential tremor (ET group) and 20 patients with Parkinson's disease (PD group). AH patients received nipradilol (6 mg per day) for more than 8 weeks. Improvement of tremor appeared within 2 or 4 weeks after the start of nipradilol therapy, and the efficacy rate, denned as "moderately effective" or over, was 42.5% in all 40 patients, while that defined as "slightly effective" or over was 87.5%. The efficacy rate tended to be higher in the ET group compared with the PD group. Mean blood pressure was significantly decreased from the 4th week after the start of treatment and heart rate was significantly reduced from the 2nd week of treatment. Laboratory examination showed no significant changes.<br>(Internal Medicine 35: 861-865, 1996)
収録刊行物
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- Internal Medicine
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Internal Medicine 35 (11), 861-865, 1996
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390001204868324608
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- NII論文ID
- 10010989708
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- NII書誌ID
- AA10827774
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- COI
- 1:CAS:528:DyaK2sXpvFOgtQ%3D%3D
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 4098999
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- PubMed
- 8968797
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可