Clinical Evaluation of Idiopathic Interstitial Pneumonia and Interstitial Pneumonia Associated with Collagen Vascular Disease using Logistic Regression Analysis.

ISHIOKA Shinichi, NAKAMURA Kimihiko, MAEDA Akihiro, HIYAMA Keiko, WATANABE Kenichiro, MAEDA Hiroyuki, HAYAKAWA Norihiko, YAMAKIDO Michio

doi:10.2169/internalmedicine.39.213

Objective To clarify the differences in the clinical features between idiopathic interstitial pneumonia (IIP) and interstitial pneumonia associated with collagen vascular diseases (CVD-IP). Methods Symptoms, radiographic findings, pulmonary function, blood chemistry data including autoantibody, and bronchoalveolar lavage fluid (BALF) findings were compared using multiple logistic regression analysis. Patients The subjects were 44 patients clinically diagnosed with IIP and 33 patients with CVD-IP. Results The clinical features related to IIP were as follows: male sex, advanced age, past history of hypertension, presence of cough, exertional dyspnea, digital clubbing, an increased level of γ-globulin, decreased lung volume on chest X-ray, and typical type according to the criteria for IIP on chest X-ray. Increased levels of rheumatoid factor and total cell number in BALF were related to CVD-IP. Conclusion These findings are considered to be useful to differentiate IIP and CVD-IP. (Internal Medicine 39: 213-219, 2000)

Clinical Evaluation of Idiopathic Interstitial Pneumonia and Interstitial Pneumonia Associated with Collagen Vascular Disease using Logistic Regression Analysis.

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