Human Herpes Virus 8-negative Primary Effusion Lymphoma (PEL) in a Patient after Repeated Chylous Ascites and Chylothorax
-
- NONAMI Atsushi
- Department of Hematology, National Kyushu Medical Center Clinical Research, National Kyushu Medical Center
-
- YOKOYAMA Toshihiro
- Department of Hematology, National Kyushu Medical Center Clinical Research, National Kyushu Medical Center
-
- TAKESHITA Morishige
- Pathology, National Kyushu Medical Center Clinical Research, National Kyushu Medical Center
-
- OHSHIMA Koichi
- Department of Pathology, School of Medicine, Fukuoka University
-
- KUBOTA Akira
- Department of Hematology, National Kyushu Medical Center Clinical Research, National Kyushu Medical Center
-
- OKAMURA Seiichi
- Department of Hematology, National Kyushu Medical Center Clinical Research, National Kyushu Medical Center
Search this article
Abstract
We describe a case of malignant lymphoma which presented in the body cavities without identifiable tumor masses. Malignant lymphoma cells showed strong atypia with prominent nuclei and basophilic cytoplasm containing vacuoles. The chromosomes showed diploidy and complex abnormalities including translocations and deletions. We diagnosed this patient with primary effusion lymphoma (PEL), even though she tested negative for human herpes virus-8 (HHV-8) which has been suggested to be causally related to PEL. Interestingly, the patient also showed complicated protein-losing enteropathy, and PEL occurred after repeated chylous ascites and chylothorax. The possible pathogenesis of this rare disease is discussed here.
Journal
-
- Internal Medicine
-
Internal Medicine 43 (3), 236-242, 2004
The Japanese Society of Internal Medicine
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390001204868662144
-
- NII Article ID
- 130000084525
-
- NII Book ID
- AA10827774
-
- COI
- 1:STN:280:DC%2BD2c3gtV2rtA%3D%3D
-
- ISSN
- 13497235
- 09182918
-
- NDL BIB ID
- 6895780
-
- PubMed
- 15098608
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- Abstract License Flag
- Disallowed