Recurrent Gastric Hemorrhaging with Large Submucosal Hematomas in a Patient with Primary AL Systemic Amyloidosis: Endoscopic and Histopathological Findings
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- IIJIMA-DOHI Naoko
- Department of Medicine, Suwa Red Cross Hospital
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- SHINJI Akihiro
- Department of Medicine, Suwa Red Cross Hospital
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- SHIMIZU Toshiki
- Department of Medicine, Suwa Red Cross Hospital
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- ISHIKAWA Sho-zou
- Department of Medicine, Suwa Red Cross Hospital
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- MUKAWA Kenji
- Department of Medicine, Suwa Red Cross Hospital
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- NAKAMURA Tomotugu
- Department of Pathology, Suwa Red Cross Hospital
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- MARUYAMA Keiko
- Department of Medicine, Suwa Red Cross Hospital
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- HOSHII Yoshinobu
- Department of Pathology, Yamaguchi University School of Medicine
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- IKEDA Shu-ichi
- Third Department of Medicine, Shinshu University School of Medicine
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Description
A 64-year-old woman who suffered intractable gastric ulcers with hemorrhaging showed huge submucosal hematomas in her stomach on the endoscopic examination. Since gastric mucosal biopsy revealed amyloid deposition and IgG λ type M protein was detectable in her serum, she was diagnosed as having primary AL systemic amyloidosis. The gastric hemorrhages did not improve despite intensive medication, so total gastrectomy was performed, resulting in an unfavorable outcome. Massive deposition of amyloid with A λ immunoreactivity was seen on the submucosal vessels in her stomach. This is a rare primary AL systemic amyloidosis case showing recurrent and fatal gastric submucosal hematomas.
Journal
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- Internal Medicine
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Internal Medicine 43 (6), 468-472, 2004
The Japanese Society of Internal Medicine
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Details 詳細情報について
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- CRID
- 1390001204868799104
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- NII Article ID
- 130000084665
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- NII Book ID
- AA10827774
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- COI
- 1:STN:280:DC%2BD2cznvF2rtg%3D%3D
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- ISSN
- 13497235
- 09182918
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- NDL BIB ID
- 6981370
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- PubMed
- 15283181
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed