Acute Liver Damage with Characteristic Apoptotic Hepatocytes by Ingestion of Aplysia kurodai, a Sea Hare.

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  • SAKAMOTO Yoshikuni
    The Department of Gastroenterology, Kyoto Prefectural Yosanoumi Hospital
  • NAKAJIMA Tomoki
    The Department of Gastroenterology, Kyoto Prefectural Yosanoumi Hospital
  • MISAWA Shinichi
    The Department of Gastroenterology, Kyoto Prefectural Yosanoumi Hospital
  • ISHIKAWA Hiroki
    The Third Department of Internal Medicine, Kyoto Prefectural University of Medicine
  • ITOH Yoshito
    The Third Department of Internal Medicine, Kyoto Prefectural University of Medicine
  • NAKASHIMA Toshiaki
    The Third Department of Internal Medicine, Kyoto Prefectural University of Medicine
  • OKANOUE Takeshi
    The Third Department of Internal Medicine, Kyoto Prefectural University of Medicine
  • KASHIMA Kei
    The Third Department of Internal Medicine, Kyoto Prefectural University of Medicine
  • TSUJI Toshizou
    The Ohta Hospital

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Other Title
  • Acute Liver Damage with Characteristic

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Abstract

A case of acute liver damage by ingestion of Aplysia kurodai, a sea hare is reported. A 40-yearold man, complaining of vomiting and pyrexia after eating a sea hare, was admitted. Laboratory data showed mild liver damage with sustained elevations of aminotransferases. Microscopic findings in the liver biopsy specimen revealed characteristic apoptotic hepatocy tes accompanied by mitotic hepatocytes. It is suggested that bioactive substances in the sea hare might induce such apoptosis of hepatocytes in the liver.<br>(Internal Medicine 37: 927-929, 1998)

Journal

  • Internal Medicine

    Internal Medicine 37 (11), 927-929, 1998

    The Japanese Society of Internal Medicine

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