Reassessment of the Classification of the Severity in Idiopathic Pulmonary Fibrosis Using SF-36 Questionnaire

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  • OHNO Shoji
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical School, Tochigi
  • NAKAZAWA Shoko
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical School, Tochigi
  • KOBAYASHI Akira
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical School, Tochigi
  • BANDO Masashi
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical School, Tochigi
  • SUGIYAMA Yukihiko
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical School, Tochigi

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Objective To investigate whether or not the newly revised classification of the severity of idiopathic interstitial pneumonia (IIP) is appropriate with respect to quality of life (QOL).<br>Methods The association between the subscale of Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) and pulmonary function or serum marker was analyzed using Pearson′s correlation coefficient. The association between the subscale of SF-36 and the previous or newly revised classification of the severity of IIP was analyzed using Spearman′s rank correlation test.<br>Patients Forty patients with idiopathic pulmonary fibrosis (IPF) were enrolled.<br>Results The mean deviation value scores for 7 items, excluding bodily pain (BP) in SF-36 were below the national reference values. % vital capacity (VC) was correlated with the 7 items excluding BP. However, neither serum LDH nor KL-6 values were correlated with any item in SF-36. According to the new or previous classification of the severity, severity was correlated with physical function, limitation of role functioning related physical problems and general health (GH); the correlation coefficient with the new one was slightly higher than the previous one. Based on these results, we established a unique draft on the classification of the severity. %VC <70% was added as an item for the newly revised classification in our draft. In our draft, there was rank correlation between the 7 items, excluding BP, in SF-36 and severity.<br>Conclusion With respect to QOL, the newly revised classification of the severity of IIP was not satisfactory, but the hypoxemia during exercise in patients with resting PaO2 >80 Torr and reduction of VC were found to be important factors.

収録刊行物

  • Internal Medicine

    Internal Medicine 44 (3), 196-199, 2005

    一般社団法人 日本内科学会

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