A Case of Primary Biliary Cirrhosis Associated with Hashimoto's Thyroiditis, Scleroderma and Sjoegren's Syndrome.

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A 53-year-old woman was admitted because of Raynaud's phenomenon, polyarthralgia and polymyalgia. Biopsy specimens of the liver and thyroid gland revealed characteristic findings of primary biliary cirrhosis (PBC) (stage I by Scheuer's classification) and chronic thyroiditis. Her clinical features were also complicated by scleroderma (type I by Barnett's classification) and Sjögren's syndrome (Sjs) with keratoconjunctivitis sicca. Thyroid hormone replacement therapy led to improvement in thyroid function, normalization of the biliary tract enzymes and alleviation of subjective symptoms.<br>(Internal Medicine 32 : 418-421, 1992)

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  • Internal Medicine

    Internal Medicine 31 (3), 418-421, 1992

    The Japanese Society of Internal Medicine

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